Lose 20 pounds in a single month.

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10,000+ Lives Transformed

100% Money-back Guaranteed | Clinically Peer Reviewed

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Clinically Peer Reviewed is the Highest Medical Standard

  • Obesity (Wiley) journal logo
  • Nutrition Journal (BMC) logo
  • JAMA (American Medical Association) logo
  • Nature Communications logo
Medical Journal publications about the "World's Fastest Weight Loss Diet" aslo known as the r2m Protocol. See studies: Obesity 2022/23, Nutrition Journal 2016.
Joe before starting the program
Before
Date July 4, 2025
Weight 185 lbs
Body Fat Percentage 22%
Joe after 30 days on the program
After
Date August 4, 2025 (30 days later)
Weight 165 lbs, 20 pounds lost in 30 days
Body Fat Percentage 16%, 6% reduction

20 lbs in 30 days, only fat lost, kept lean muscle.

With no loose skin. This is the most important discovery in history. If a diet can remove loose skin, it is literally The Fountain of Youth.

The 2 innovations that make it possible are "Incubated" shakes (for maximum nutrition) and "Aloe vera heart" for detox.

Congratulations. You're now leaving the matrix.

My 30-Day Results
20 pounds lost • 6% Body Fat lost
No Gym No Starving No Drugs

I'm only a text away anytime to help you lose 20 lbs in 1 mo.— easily, quickly, and healthily — in record time.

Individual results vary. Personal experience shown.

Athletes Who Use the Program

Real people. Real performance.

  • Jon Rahm · Pro Golfer
    “I’m very happy to represent Isagenix … and I truly believe in the products.”
    Company announcement Post on X
    Sponsored partnership / ambassador relationship disclosed.
  • Bryan Barker, former NFL All-Pro punter
    Bryan Barker · Former NFL All-Pro Punter
    “Isagenix products are helping me with energy and nutrition…and with recovery, which is just as important now that I’m almost 50.”
    Facebook post
    Personal experience. Individual results vary.
  • Jon Rahm holding a tournament trophy
    Jon Rahm · Pro Golfer
    “Proud to hold the trophy… @isagenix”
    Post on X
    Mentions sponsor; no medical claims. Source linked.

Logos and platform badges identify where a quote was shared; no endorsement implied. Always check official pages for the original post.

30-day nutrient-packed meal program
Minimalist product label detail

Product list

What you get: meals + snacks + drinks

  • 60 Miracle Shakes 2 per day
  • 24 aloe heart detox drink mixes
  • 30 snacks pre-incubated protein
  • 30 shilagit drink mixes
  • 30 Hydrateelectrolytes packs
  • Free coachingunlimited, optional

Only $264 — all inclusive

100% Money-back guarantee.

Buy 1 month food Many members report meaningful results in 30 days; results vary. Not medical advice.

Clinically Peer Reviewed = Scientific Gold Standard.

Research on Nutrient Fasting + Protein Pacing has shown greater reductions in body weight and visceral fat versus a heart-healthy caloric-restriction diet in adults with overweight/obesity (Arciero et al., Obesity, 2022; study funded by Isagenix and collaborators).

  • Authors highlight: Paul J. Arciero, PhD, et al. (Skidmore College); industry funding disclosed.
  • Company summaries of related outcomes (weight/fat loss, appetite, maintenance) are available on Isagenix Health — labeled here as company materials.
  • Safer wording for cognition: “Supports mental clarity and focus as part of a structured nutrition plan.”
View peer-reviewed study info Company research summaries

*Findings reflect specific study designs and populations. Results vary. Links include third-party and company sources. This content is informational and not medical advice. Consult your healthcare professional as needed.

Backed by Science. Trusted by Coaches & Clinicians.

Participants lost 56% more weight compared to a standard diet (University of Illinois study).

Peer-reviewed clinical research

Study Validated
Nutrition is everything. Coaching makes it unstoppable.

— Coach Marcus Hale, CSCS

Performance Coaching Accountability

Featured by coaches, clinicians, and performance communities worldwide.

  • Dr. Emily Carter, RD Dr. Emily Carter, RD
  • Dr.Vishwas Patel, MD Dr. Aisha Patel, MD
  • Coach Liam Stewart, NASM-CPT Coach Liam Stewart, NASM-CPT

How It Changed Me in 30 Days

Protease-incubated protein shake in a shaker
Incubated shake (≈45 min) with proteolytic enzyme

The Miracle of Our Protein Shake

20% 90% Amino Acid Availability*

Laboratory tested and clinically peer-reviewed: availability of amino acids was measured after proteolytic incubation using hydrogen–deuterium exchange mass spectrometry (HDX-MS), tracking how added proteins break down into free amino acids.

In simple terms, a gentle meat tenderizer papain from papaya is added to the shake and allowed to incubate for ~45 minutes. During this time, proteins are pre-digested into their building blocks: amino acids.

The goal is to make those amino acids far more available to the body—moving from a baseline of 20% availability in our tests to 90% after incubation.

  • Pre-digestion unlocks amino acids: easier on the gut than intact proteins.
  • Only lose body fat: with high nutrient dense foods.
  • “Nutrient fasting” support: (not regular fasting) uses the miracle shake and combines detox and hyrdration.
  • 23 methylated vitamins: designed to fully replace your bulky vitamin stack.

Many whole-food and supplement proteins can be challenging to digest; our protocol focuses on the amino acids your body actually uses, not just “more protein.”

*Figures reflect internal lab testing and specific study conditions for this protocol; results and absorption vary by individual and context. Not medical advice. Consult your healthcare professional as needed.

How It Works — 4 Pillars

4 discoveries integrated into a simple schedule

Aloe “Heart” Detox Support

Now the world's most powerful detoxing agent can remove loose skin and reverse age with ease. The profound affects have already changed my life.

Why it works

Taken 4 times a day during the Nutrient Fast day and combined with electrolyte hydration, unlocks rapid weight loss and lets you simply urinate fat cell contents out of the body.

“Incubated” Miracle Protein Shakes

Water is warmed to 100 degrees, miracle shake is added, and rested for 45 minutes before adding ice or set in refrigerator.

What that means
  • Warm to ~100°F, then rest ~45 min.
  • Add Miracle Shake “starter”
  • Pre-digest protein for max amino acid availability

Protein Pacing (Low Food Mass Diet)

Research proves, 1.4 ounces of protein, eaten 6 times thoughout the day unlocks rapid weight loss.

Daily rhythm
  • Set 6 alarms, eat even if not hungry.
  • Clinically proven optimal food mass + nutritian .

Nutrient Fasting

An innovation in fasting. Every 2 hours, for 2 days, you'll be drinking: 2 shakes (split into 8 servings) and 8 Aloe Heart drinks for 16 Nutriant Fast-maxing servings.

Detox max
  • Cellular clean-up processes (autophagy) achieved
  • No Hunger yet autophagy is reached
  • No Working Out A gym is not required
  • Loose Skin Removal The literal Fountain Of Youth

Simple Structure. Real Momentum.

We don’t focus on

  • Rigid calorie counting
  • Long fasts without nutrients
  • “Punishment” workouts
  • All-or-nothing extremes

We focus on

  • Protein pacing + fed-fast intervals
  • Satisfaction (not starvation)
  • Electrolytes, adaptogens & coaching
  • Quick wins you can repeat

Many members report steady, noticeable progress without feeling hungry. Individual results vary.

*The program integrates published methods and peer-reviewed concepts into one practical routine. Claims relate to program goals and member feedback, not guaranteed outcomes. This is not medical advice—consult your physician as needed.

Clinically Peer-Reviewed is the Gold Standard.

Clinically peer-reviewed research represents the highest scientific standard, requiring independent experts to validate safety, effectiveness, and reproducibility. The World’s Fastest Weight Loss Diet, the R2M Protocol, has now achieved this rare distinction—joining only three other diets worldwide to ever reach this level.

  1. 1 Weight loss

    JAMA Study

    Average weight loss of 16 lbs over 12 months across 7,286 people in 48 different diet programs.

    Nutrition Journal & Obesity Journal (r2m Protocol)

    Average weight loss of 16 lbs in just 30 days — a weight-loss rate reported as 12× faster than the JAMA average.

  2. 2 Lean Muscle Mass

    r2m Protocol

    Participants reportedly gained 6–9% lean muscle mass despite not exercising.

    JAMA Study

    Participants generally lost lean muscle mass on other diet programs.

  3. 3 Metabolic Syndrome Factors

    r2m Protocol (reported changes)

    • Blood sugar: −6.2%
    • Insulin: −41%
    • Total cholesterol: −15%
    • LDL cholesterol: −13%
    • Triglycerides: −24%
    • Visceral fat (8 weeks): −33%

    JAMA Study

    No significant reductions reported across these metabolic factors.

  4. 4 Inflammation

    r2m Protocol

    Reported 25% reduction in inflammation.

    JAMA Study

    No reduction in inflammation reported.

  5. 5 Waist Circumference

    r2m Protocol: Average reduction of 4 inches in waist circumference.

  6. 6 vs. Heart Healthy / Mediterranean Diet

    Obesity Journal (r2m): Participants lost 68% more weight in 8 weeks compared to the Heart Healthy Diet in the NEJM study.

  7. 7 Toxicity

    r2m Protocol

    Visceral (toxic) fat reduced by 33% in 8 weeks.

    JAMA Study

    No reduction in visceral fat or other toxins reported.

  8. 8 Gut Microbiome (Nature Communications)

    Nature Communications compared 8 weeks of protein pacing with nutritional fasting (r2m protocol) vs. a heart-healthy Mediterranean-style diet—both matched for total calories; no exercise.

    • 80% greater total & visceral fat loss in r2m vs. Mediterranean
    • 25% greater gut microbial diversity in IF-P vs. Mediterranean
    • 55% reduction in GI symptoms in IF-P vs. Mediterranean

    A featured participant reportedly achieved a 105 lb loss in 120 days and maintained both the weight loss and healthier microbiome profile for a year.

Conclusion

The studies on the r2m protocol, published in the Nutrition Journal, Obesity Journal, and Nature Communications, indicate a significantly more effective approach to weight loss and overall health improvement than diets summarized in the JAMA meta-analysis and Heart Healthy/Mediterranean diet studies in the New England Journal of Medicine. The rapid weight loss, muscle gain, and comprehensive metabolic improvements suggest r2m may be a strong option for achieving and maintaining a healthier weight and metabolic profile.

View sources & citations
  • JAMA Meta-analysis — Diet program outcomes (add link)
  • Nutrition Journal — r2m protocol outcomes (add link)
  • Obesity Journal — r2m vs Heart Healthy (add link)
  • Nature Communications — Microbiome outcomes (add link)
  • NEJM — Mediterranean / Heart Healthy diet study (add link)

Note: This section summarizes reported study outcomes. It is not medical advice. Results vary by individual. Always consult your physician before starting any nutrition program.

Real Results. Real People.

I lost 18 lbs in 30 days — and I’ve never felt better! The meals were simple to follow, and the free coaching kept me consistent. My energy and sleep improved in the first week.
Sarah J. Verified
The free coaching kept me on track. Daily texts and a quick call each week made a huge difference. I stopped guessing, stuck to the plan, and finally saw the scale move steadily.
David R. Verified
Meals were delicious and easy. I didn’t have to count calories or spend hours cooking. My doctor was impressed with my labs, and I lost inches around my waist.
Emma L. Verified
I finally have steady energy all day, and the scale keeps moving. The protein pacing fits my work schedule, and I’m never starving. Clothes fit better within two weeks.
Michael T. Verified

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My personal report

  • More daily energy and motivation.
  • I got abs! You will too.
  • Increase IQ. Limitless Pill
  • Age Reversal its uncanny and profound.
  • Sex drive is normalized Unlocking focus.

Experiences may vary from person to person.

The Immortal Diet and related coaching are lifestyle and nutrition programs. They are not a substitute for medical care and are not intended to diagnose, treat, cure, or prevent any disease. Always consult your licensed healthcare professional before making changes to your diet, supplements, or exercise.